Ascorbic Acid + Sodium Ascorbate + Zinc Chewable Tablets

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Therapeutic Indication

Antiviral therapy
Cardiovascular diseases
Age-related macular degeneration (AMD) and cataracts
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Ascorbic Acid + Sodium Ascorbate + Zinc Chewable

Tablet

Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. Humans, unlike most animals, are unable to synthesize vitamin C endogenously, so it is an essential dietary component. Fruits and vegetables are the best sources of vitamin C. Citrus fruits, tomatoes and tomato juice, and potatoes are major contributors of vitamin C. Other good food sources include red and green peppers, kiwifruit, broccoli, strawberries, Brussels sprouts, and cantaloupe.
Acute vitamin C deficiency leads to scurvy. Initial symptoms can include fatigue (probably the result of impaired carnitine biosynthesis), malaise, and inflammation of the gums. As vitamin C deficiency progresses, collagen synthesis becomes impaired and connective tissues become weakened, causing petechiae, ecchymoses, purpura, joint pain, poor wound healing, hyperkeratosis, and corkscrew hairs. Additional signs of scurvy include depression as well as swollen, bleeding gums and loosening or loss of teeth due to tissue and capillary fragility. Iron deficiency anaemia can also occur due to increased bleeding and decreased nonheme iron absorption secondary to low vitamin C intake. In children, bone disease can be present. Left untreated, scurvy is fatal. Zinc is considered as trace element as it is required in a very minute quantity. Zinc is vital for a healthy immune system, correctly synthesizing DNA, promoting healthy growth during childhood, and healing wounds. A wide variety of foods contain zinc. Oysters contain more zinc per serving than any other food, but red meat and poultry provide the majority of zinc in the American diet. Other good food sources include beans, nuts, certain types of seafood (such as crab and lobster), whole grains, fortified breakfast cereals, and dairy products.

Zinc deficiency is characterized by growth retardation, loss of appetite, and impaired immune function. In more severe cases, zinc deficiency causes hair loss, diarrhoea, delayed sexual maturation, impotence, hypogonadism in males, and eye and skin lesions. Weight loss, delayed healing of wounds, taste abnormalities, and mental lethargy can also occur

Speciality Vitamin C Supplement | Zinc Supplement | Antioxidant Therapy
Tags Vitamin C | Sodium Ascorbate | Zinc | Immunity | Antioxidant | Chewable Tablet
Strength
  • Ascorbic Acid 100 mg
  • Sodium Ascorbate 450 mg
  • Zinc Citrate 5 mg
Packing Size
  • 10 Tablets

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Mechanism

Vitamin C is required for the biosynthesis of collagen, L-carnitine, and certain neurotransmitters; vitamin C is also involved in protein metabolism. Collagen is an essential component of connective tissue, which plays a vital role in wound healing. Vitamin C is also an important physiological antioxidant and has been shown to regenerate other antioxidants within the body, including alpha-tocopherol (vitamin E). Vitamin C acts by limiting the damaging effects of free radicals through its antioxidant activity, might help prevent or delay the development of certain cancers, cardiovascular disease, and other diseases in which oxidative stress plays a causal role. In addition to its biosynthetic and antioxidant functions, vitamin C plays an important role in immune function and improves the absorption of nonheme iron, the form of iron present in plant-based foods. Insufficient vitamin C intake causes scurvy, which is characterized by fatigue or lassitude, widespread connective tissue weakness, and capillary fragility.

Zinc: It help is synthesis of more than 70 different enzymes. Zinc containing enzymes regulates metabolism of carbohydrates, lipids, and proteins. Zinc fastens wound healing; maintain normal growth rates, balance skin hydration and the senses of taste and smell. It assists normal growth and tissue repair. It boosts cell mediated immunity. It is poorly absorbed when given orally. Zinc is well distributed in tissues like skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Zinc is mainly excreted through intestine and only 2% loss in the urine.
Why Formulation Contains Sodium Ascorbate Along With Ascorbic Acid? Ascorbic Acid is also known as Vitamin C which is acidic in nature. Sodium ascorbate is the mineral salt of ascorbic acid. The formulation contains both ‘ascorbic acid’ and ‘sodium ascorbate’ so as to improve the absorption of ascorbic acid in all types of stomach conditions as pure ascorbic acid can be too acidic for some people's stomach (and cause heartburn). Sodium ascorbate, a mineral ascorbate can be great in sensitive stomachs and may have a slight GI absorption advantage over ascorbic acid and can prevent side effects of ascorbic acid at high doses.

Pharmacokinetics

  • Absorption: Vitamin C and Zinc are absorbed in the small intestine; bioavailability enhanced when taken with food.
  • Distribution: Vitamin C widely distributed in tissues; Zinc stored in muscle and bone.
  • Metabolism: Vitamin C metabolized to oxalate; Zinc undergoes minimal metabolism.
  • Elimination: Vitamin C excreted via urine; Zinc excreted via feces and urine.
  • Half-life: Vitamin C ~8–12 hours; Zinc varies depending on body stores.

Side Effects

    li>Mild gastrointestinal upset (nausea, diarrhea).
  • Metallic taste due to zinc.
  • Rare allergic reactions.

Contraindication

  • Hypersensitivity to Vitamin C or Zinc.
  • Patients with hemochromatosis (risk of iron overload).
  • Severe renal impairment (risk of oxalate kidney stones).

Interaction

  • Antibiotics (tetracyclines, quinolones): Zinc may reduce absorption.
  • Iron supplements: Vitamin C enhances absorption; monitor iron levels.
  • Copper supplements: Zinc may reduce copper absorption.

Warning and Precautions

  • Use under medical supervision in patients with kidney disease.
  • High doses of Vitamin C may cause kidney stones.
  • Pregnant and lactating women should consult a physician before use.
  • Store below 25°C, away from moisture and sunlight.
  • Keep out of reach of children.

Dosage

As directed by the Dietician.